Will Ozone Kill Roaches and Bugs?
Yes, ozone will kill roaches and bugs, but it is not intended for pest control. More than a few professional ozone services have arrived on the job to find dozens of roaches "Belly Up" after a treatment. Roaches, and bugs in general, are reclusive and may run from any threat to return later. So, treating for bugs requires more than a passing knowledge of insects. It is likely, however, that roaches, spiders, and such will die off during a serious ozone treatment. It is also probable that they will return unless further steps are taken to deal with pests.
One of the practical steps is to check the perimeter of the house for ways bugs get in. Seal and caulk around pipe, wires, windows, and any potential opening. It will surprise you how narrow a crack bugs can navigate. And, get rid of any trash, wood piles, or debris around the outside of the house. In particular, do not put your trash can at the back door. This is like a waystation on their way inside.
Second, cleaning is the number one bug defense. Bugs are after food and or habitat. Cleaning up is extremely important. Vacuum rugs when kids leave crumbs everywhere. Seal up trash bags, and do not leave food in the trash open through the night. Like the Gremlin movie, if you feed then after midnight, they will rapidly populate.
Replace cardboard boxes with plastic containers. This will prevent mold and mildew on cardboard, and may preserve your goods against moisture. And, do not leave lumber or wood in the basement where it will rot or be a food source for termites.
When you have done all the above, you may want to try a serious ozone treatment. This is not some 5000 mg/h machine, but something that is powerful enough to create the ozone shock. At this point, you are getting rid of odors, killing mold and mildew, sanitizing, and probably killing bugs. Treatments can last three to six hours for maximum impact. Then, evaluate the process.
If you are satisfied with the results, try sprinkling some diatomaceous earth in hidden and obscure places. It is not poisonous or toxic, but there are microscopic edges in the powder that cut into the joints of all kinds of bugs to kill them. This secondary process is meant to keep the bugs from returning.